Agnete Kirkeby

Our research

The Kirkeby Lab studies the factors involved in human neural subtype specification in order to enable production of specific neurons for understanding and treating neurological diseases. We use stem cells to produce specific subtypes of human neurons.

Focus is to develop novel stem cell transplantation therapies for neurodegenerative diseases as well as to use the stem cells as a tool to understand the pathogenesis of brain disorders.

Aims

• To develop novel stem cell-based transplantation therapies for neurodegenerative diseases.

Strengths of the group

All our projects are built on a close collaboration between various group members with expertise in stem cell biology, xenotransplantation, rodent behavioral testing and bioinformatics for investigating the function and quality of human stem cell-derived brain grafts. 

Impact

Based on our research, we have brought a novel stem cell-based treatment for Parkinson’s Disease from preclinical development to clinical trial, and the first patient has been transplanted with our novel stem cell product in February 2023.

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| Research Output

Affiliations

• Wallenberg Center for Molecular Medicine
• Dept for Experimental Medical Science
• The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), University of Copenhagen

Social media

• Scopus
• Web of Science
• Orcid
• Twitter